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Article

Prevalence and molecular basis of resistance to echinocandins among clinical Candida glabrata isolates in Guangdong province, China.

BMC microbiology - 20 Aug 2025

Lin Weihong, Peng Yaqin, Xiang Bo, Fang Jingchun, Ye Junkai, Guo Penghao

Abstract excerpt

BACKGROUND: Infections caused by Candida glabrata have raised increasing concerns, particularly due to the increasing resistance to echinocandins. OBJECTIVES: This study investigated echinocandins susceptibility trends in C. glabrata isolates and explored the mechanisms driving resistance. METHODS: We analyzed 418 strains of C. glabrata derived from hospitalized patients. Phenotypic resistance was assessed, and...

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Identifiers

PMID: 40830434
DOI: 10.1186/s12866-025-04275-y
PMCID: PMC12366116

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