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Article

Biochemistry and physiology of hexose-6-phosphate knockout mice.

Molecular and cellular endocrinology - 10 Apr 2011

Zielinska Agnieszka E, Walker Elizabeth A, Stewart Paul M, Lavery Gareth G

Abstract excerpt

Hexose-6-phosphate dehydrogenase (H6PDH) has emerged as an important factor in setting the redox status of the endoplasmic reticulum (ER) lumen. An important role of H6PDH is to generate a high NADPH/NADP(+) ratio which permits 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) to act as an oxo-r...

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Identifiers

PMID: 21146583
DOI: 10.1016/j.mce.2010.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21146583-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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