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Article

Glucose-6-phosphate dehydrogenase--from oxidative stress to cellular functions and degenerative diseases.

Redox report : communications in free radical research - 1 Jan 2007

Ho Hung-yao, Cheng Mei-ling, Chiu Daniel Tsun-yee

Abstract excerpt

Glucose-6-phosphate dehydrogenase (G6PD), the first and rate-limiting enzyme of the pentose phosphate pathway, is indispensable to maintenance of the cytosolic pool of NADPH and thus the cellular redox balance. The role of G6PD as an antioxidant enzyme has been recognized in erythrocytes for a long time, as its deficiency is associated with neonatal jaundice, drug- or infection-mediated hemolytic crisis, favism...

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PMID: 17623517
DOI: 10.1179/135100007X200209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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