Article

Hematologic and systemic metabolic alterations due to Mediterranean type II G6PD deficiency in mice

2021-05-31

Abstract excerpt

Deficiency of Glucose 6 phosphate dehydrogenase (G6PD) is the single most common enzymopathy, present in approximately 400 million humans (e.g. 5% of humans). Its prevalence is hypothesized to be due to conferring resistance to malaria. However, G6PD deficiency also results in hemolytic sequelae from oxidant stress. Moreover, G6PD deficiency is associated with kidney disease, diabetes, pulmonary hypertension, immu...

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Literature Corpus work: afb72d44-bd5e-5654-bc69-e0db759a3d03
DOI: 10.1101/2021.05.31.446353

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