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Article

Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells.

DNA repair - 7 Mar 2011

Ha Kyungsoo, Takeda Yoshihiko, Dynan William S

Abstract excerpt

PSF (gene name SFPQ) is a member of a small family of proteins with dual functions in RNA biogenesis and DNA repair. PSF and PSF-containing complexes stimulate double-strand break repair in cell free systems, most likely via direct interaction with the repair substrate. Prior in vitro studies are, however, insufficient to demonstrate whether PSF contributes to DNA repair in living cells. Here, we investigate the...

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Source

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Identifiers

PMID: 21144806
DOI: 10.1016/j.dnarep.2010.11.009
PMCID: PMC3046316

Genes

SFPQ
NONO
PSPC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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