Article
The deinococcal DdrB protein is involved in an early step of DNA double strand break repair and in plasmid transformation through its single-strand annealing activity.
DNA repair - 10 Dec 2011
Bouthier de la Tour Claire, Boisnard Stéphanie, Norais Cédric, Toueille Magali, Bentchikou Esma, Vannier Françoise, Cox Michael M, Sommer Suzanne, Servant Pascale
Abstract excerpt
The Deinococcus radiodurans bacterium exhibits an extreme resistance to ionizing radiation. Here, we investigated the in vivo role of DdrB, a radiation-induced Deinococcus specific protein that was previously shown to exhibit some in vitro properties akin to those of SSB protein from Escherichia coli but also to promote annealing of single stranded DNA. First we report that the deletion of the C-terminal motif of...
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