Article
Mechanism for regulation of the putrescine utilization pathway by the transcription factor PuuR in Escherichia coli K-12.
Journal of bacteriology - 1 Jul 2012
Nemoto Naoki, Kurihara Shin, Kitahara Yuzuru, Asada Kei, Kato Kenji, Suzuki Hideyuki
Abstract excerpt
In Escherichia coli, putrescine is metabolized to succinate for use as a carbon and nitrogen source by the putrescine utilization pathway (Puu pathway). One gene in the puu gene cluster encodes a transcription factor, PuuR, which has a helix-turn-helix DNA-binding motif. DNA microarray analysis of an E. coli puuR mutant, in which three amino acid residues in the helix-turn-helix DNA binding motif of PuuR were...
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