Article
Endothelial lipase (EL) and EL-generated lysophosphatidylcholines promote IL-8 expression in endothelial cells.
Atherosclerosis - 1 Feb 2011
Riederer Monika, Lechleitner Margarete, Hrzenjak Andelko, Koefeler Harald, Desoye Gernot, Heinemann Akos, Frank Saša
Abstract excerpt
OBJECTIVE: Previously we identified palmitoyl-lysophosphatidylcholine (LPC 16:0), as well as linoleoyl-, arachidonoyl- and oleoyl-LPC (LPC 18:2, 20:4 and 18:1) as the most prominent LPC species generated by the action of endothelial lipase (EL) on high-density lipoprotein (HDL). In the present st...
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