Article

Endothelial lipase is a major determinant of HDL level

2003-02-01

Abstract excerpt

A new member of the lipase gene family, initially termed endothelial lipase (gene nomenclature, LIPG; protein, EL), is expressed in a variety of different tissues, suggesting a general role in lipid metabolism. To assess the hypothesis that EL plays a physiological role in lipoprotein metabolism in vivo, we have used gene targeting of the native murine locus and transgenic introduction of the human LIPG locus in m...

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Literature Corpus work: b2cf604d-9bca-5f13-ab67-d33959ac963a
DOI: 10.1172/jci200316306

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