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Article

Endothelial lipase is a major determinant of HDL level.

The Journal of clinical investigation - 1 Feb 2003

Ishida Tatsuro, Choi Sungshin, Kundu Ramendra K, Hirata Ken-Ichi, Rubin Edward M, Cooper Allen D, Quertermous Thomas

Abstract excerpt

A new member of the lipase gene family, initially termed endothelial lipase (gene nomenclature, LIPG; protein, EL), is expressed in a variety of different tissues, suggesting a general role in lipid metabolism. To assess the hypothesis that EL plays a physiological role in lipoprotein metabolism in vivo, we have used gene targeting of the native murine locus and transgenic introduction of the human LIPG locus in...

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Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12569160
DOI: 10.1172/JCI16306
PMCID: PMC151857

Genes

LIPG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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