Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for epistatic interactions in antiepileptic drug resistance.

Journal of human genetics - 1 Jan 2011

Kim Myeong-Kyu, Moore Jason H, Kim Jong-Ki, Cho Ki-Hyun, Cho Yong-Won, Kim Yo-Sik, Lee Min-Cheol, Kim Young-Ok, Shin Min-Ho

Abstract excerpt

To investigate the epistatic interactions involved in antiepileptic drug (AED) resistance, 26 coding single-nucleotide polymorphisms (SNPs) were selected from 16 candidate genes. A total of 200 patients with drug-resistant localization-related epilepsy and 200 patients with drug-responsive locali...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticonvulsants
Share to Case-Control Studies
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Epilepsy

Share to Epistasis, Genetic

Share to Validation Studies as Topic

Share to Young Adult

Source

Identifiers

PMID: 21124337
DOI: 10.1038/jhg.2010.151

Genes

GABRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21124337-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for epistatic interactions in antiepileptic drug resistance.PMID 21124337Read ↗

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.Semantic proximity Read ↗

Genetics of drug resistance in epilepsy.Semantic proximity Read ↗

Genetic variations associated with pharmacoresistant epilepsy (Review).Semantic proximity Read ↗

The roles of variants in human multidrug resistance (MDR1) gene and their haplotypes on antiepileptic drugs response: a meta-analysis of 57 studies.Semantic proximity Read ↗

Association between ABCB1 C3435T polymorphism and antiepileptic drug resistance in epilepsy: An updated meta-analysis based on 62 studies.Semantic proximity Read ↗

Genetics of drug resistance.Semantic proximity Read ↗

Relationship between ABCB1 3435TT genotype and antiepileptic drugs resistance in Epilepsy: updated systematic review and meta-analysis.Semantic proximity Read ↗

The role of common variation in drug transporter genes in refractory epilepsy.Semantic proximity Read ↗

GABRG2, rs211037 is associated with epilepsy susceptibility, but not with antiepileptic drug resistance and febrile seizures.Semantic proximity Read ↗

Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1.Semantic proximity Read ↗

The ABCB1-C3435T polymorphism likely acts as a risk factor for resistance to antiepileptic drugs.Semantic proximity Read ↗

Multiobjective differential evolution-based multifactor dimensionality reduction for detecting gene-gene interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.