Article
Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.
Journal of Korean medical science - 1 Feb 2009
Jang Sin-Young, Kim Myeong-Kyu, Lee Kee-Ra, Park Man-Seok, Kim Byeong-Chae, Cho Ki-Hyun, Lee Min-Cheol, Kim Yo-Sik
Abstract excerpt
The pathogenesis of antiepileptic drug (AED) resistance is multifactorial. However, most candidate gene association studies typically assess the effects of candidate genes independently of each other, which is partly because of the limitations of the parametric-statistical methods for detecting the gene-to-gene interactions. A total of 200 patients with drug-resistant epilepsy and 200 patients with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
