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Article

GABRG2, rs211037 is associated with epilepsy susceptibility, but not with antiepileptic drug resistance and febrile seizures.

Pharmacogenetics and genomics - 1 Nov 2013

Balan Shabeesh, Sathyan Sanish, Radha Saradalekshmi K, Joseph Vijai, Radhakrishnan Kurupath, Banerjee Moinak

Abstract excerpt

OBJECTIVE: Several antiepileptic drugs (AEDs) are known to target the GABA(A) receptor through positive allosteric modulation of the receptors, thereby enhancing GABA(A) receptor-mediated inhibition. The large diversity of GABA(A) receptors has been reported in the central nervous system; some of these have been implicated in epilepsy susceptibility and AED resistance, which we aimed to examine. MATERIALS AND...

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Topics

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Share to Anticonvulsants
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epilepsy, Temporal Lobe

Share to Hippocampus

Share to Myoclonic Epilepsy, Juvenile

Share to Receptors, GABA-A

Share to Sclerosis

Share to Seizures, Febrile

Source

Identifiers

PMID: 24061200
DOI: 10.1097/FPC.0000000000000000

Genes

GABRG2
GABRA1
GABRA6
GABRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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