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Genetic variations associated with pharmacoresistant epilepsy (Review).

Molecular medicine reports - 1 Apr 2020

Cárdenas-Rodríguez Noemí, Carmona-Aparicio Liliana, Pérez-Lozano Diana L, Ortega-Cuellar Daniel, Gómez-Manzo Saúl, Ignacio-Mejía Iván

Abstract excerpt

Epilepsy is a common, serious neurological disorder worldwide. Although this disease can be successfully treated in most cases, not all patients respond favorably to medical treatments, which can lead to pharmacoresistant epilepsy. Drug‑resistant epilepsy can be caused by a number of mechanisms that may involve environmental and genetic factors, as well as disease‑ and drug‑related factors. In recent years,...

Topics

Drug Resistance
Epilepsy
Genetic Variation
Humans

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32319641
DOI: 10.3892/mmr.2020.10999
PMCID: PMC7057824

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