Article
The role of common variation in drug transporter genes in refractory epilepsy.
Expert opinion on pharmacotherapy - 1 Jul 2005
Soranzo Nicole, Goldstein David B, Sisodiya Sanjay M
Abstract excerpt
Resistance to antiepileptic drugs (AEDs) is one of the most serious clinical problems in epilepsy, and along with AED teratogenicity, perhaps the major concern of epilepsy pharmacogenetics. Studying the genetics of drug resistance in epilepsy is important, as it may identify or confirm key mechanisms underlying this phenomenon that have real clinical importance; it might also offer insights into its prediction...
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