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Article

EGF +61A>G polymorphism and gastrointestinal cancer risk: a HuGE review and meta-analysis.

Gene - 25 Apr 2013

Piao Ying, Liu Zhaozhe, Ding Zhenyu, Xu Long, Guo Fang, Sun Qingqing, Xie Xiaodong

Abstract excerpt

Emerging evidences from preclinical and clinical studies have shown that epidermal growth factor (EGF) has some effectiveness against endogenously arising carcinogenesis. Functional +61A>G polymorphism (rs4444903 A>G) in the promoter region of the EGF gene was observed to modulate EGF levels, thus affecting the susceptibility to gastrointestinal cancer; but individually published studies showed inconclusive...

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Source

Identifiers

PMID: 23403233
DOI: 10.1016/j.gene.2013.01.057

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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