Article
Association of specific genetic polymorphisms with age-related macular degeneration in a northern Chinese population.
Ophthalmic genetics - 1 Sept 2014
Zhuang Wenjuan, Li HuiPing, Liu Yani, Zhao Jingjing, Ha Shaoping, Xiang Wei, Bai Xuewei, Li Zili, Han Ying, Sheng Xunlun
Abstract excerpt
PURPOSE: The associations between genetic variants located in CFH, CFB, ARMS2 and HTRA1 and the risk of age-related macular degeneration (AMD) in a northern Chinese population were investigated. METHODS: A case-control association study of 150 AMD patients and 145 ethnicity- and gender-matched controls were recruited. Genomic DNA was prepared from peripheral blood after the participants underwent comprehensive...
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