Article
Genomic aspects of age-related macular degeneration.
Biochemical and biophysical research communications - 19 Sept 2014
Horie-Inoue Kuniko, Inoue Satoshi
Abstract excerpt
Age-related macular degeneration (AMD) is a major late-onset posterior eye disease that causes central vision to deteriorate among elderly populations. The predominant lesion of AMD is the macula, at the interface between the outer retina and the inner choroid. Recent advances in genetics have revealed that inflammatory and angiogenic pathways play critical roles in the pathophysiology of AMD. Genome-wide...
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