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Article

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.

BMC cancer - 30 Nov 2010

Holstege Henne, Horlings Hugo M, Velds Arno, Langerød Anita, Børresen-Dale Anne-Lise, van de Vijver Marc J, Nederlof Petra M, Jonkers Jos

Abstract excerpt

BACKGROUND: Basal-like breast cancers (BLBC) are aggressive breast cancers for which, so far, no targeted therapy is available because they typically lack expression of hormone receptors and HER2. Phenotypic features of BLBCs, such as clinical presentation and early age of onset, resemble those o...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 21118481
DOI: 10.1186/1471-2407-10-654
PMCID: PMC3002929

Genes

BRCA1
PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21118481-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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