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Article

FOXC1 identifies basal-like breast cancer in a hereditary breast cancer cohort.

Oncotarget - 15 Nov 2016

Johnson Jeff, Choi Michael, Dadmanesh Farnaz, Han Bingchen, Qu Ying, Yu-Rice Yi, Zhang Xiao, Bagaria Sanjay, Taylor Clive, Giuliano Armando E, Amersi Farin, Cui Xiaojiang

Abstract excerpt

Breast cancers arising in the setting of the hereditary breast cancer genes BRCA1 and BRCA2 are most commonly classified as basal-like breast cancer (BLBC) or luminal breast cancer, respectively. BLBC is an aggressive subtype of breast cancer associated with liver and lung metastases and poorer prognosis than other subtypes and for which chemotherapy is the only systemic therapy. Multiple immunohistochemical...

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Source

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Identifiers

PMID: 27708239
DOI: 10.18632/oncotarget.12370
PMCID: PMC5342773

Genes

FOXC1
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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