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Article

Basal-like subtype and BRCA1 dysfunction in breast cancers.

International journal of clinical oncology - 1 Oct 2008

Miyoshi Yasuo, Murase Keiko, Oh Koushi

Abstract excerpt

Basal-like breast cancers are characterized by their unique expression profile, with the frequent loss of BRCA1, caused by such mechanisms as promoter methylation and the overexpression of high-mobility group proteins of the A type 1 or inhibitor of differentiation 4. Clinicopathologically, basal-like cancers are estrogen receptor-, progesterone receptor-, and human epidermal growth factor receptor type 2...

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Source

Identifiers

PMID: 18946749
DOI: 10.1007/s10147-008-0831-x

Genes

BRCA1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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