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Article

Mitochondrial transcription factors TFAM and TFB2M regulate Serca2 gene transcription.

Cardiovascular research - 1 Apr 2011

Watanabe Atai, Arai Masashi, Koitabashi Norimichi, Niwano Kazuo, Ohyama Yoshiaki, Yamada Yoshihumi, Kato Noriko, Kurabayashi Masahiko

Abstract excerpt

AIMS: Sarco(endo)plasmic reticulum Ca²(+)-ATPase 2a (SERCA2a) transports Ca²(+) by consuming ATP produced by mitochondrial respiratory chain enzymes. Messenger RNA (mRNA) for these enzymes is transcribed by mitochondrial transcription factors A (TFAM) and B2 (TFB2M). This study examined whether TFAM and TFB2M coordinately regulate the transcription of the Serca2 gene and mitochondrial genes. METHODS AND RESULTS:...

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Source

Identifiers

PMID: 21113058
DOI: 10.1093/cvr/cvq374

Genes

TFAM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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