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Mechanisms of mammalian mitochondrial transcription

16 Jul 2019

Abstract excerpt

Numerous age-related human diseases have been associated with deficiencies in cellular energy production. Moreover, genetic alterations resulting in mitochondrial dysfunction are the cause of inheritable disorders commonly known as mitochondrial diseases. Many of these deficiencies have been directly or indirectly linked to deficits in mitochondrial gene expression. Transcription is an essential step in gene...

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PMID: 31309618
DOI: 10.1002/pro.3688

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