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Article

Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells.

American journal of physiology. Cell physiology - 1 May 2004

Freyssenet Damien, Irrcher Isabella, Connor Michael K, Di Carlo Martino, Hood David A

Abstract excerpt

Cytochrome c expression and mitochondrial biogenesis can be invoked by elevated intracellular Ca(2+) in muscle cells. To characterize the potential role of Ca(2+) as a messenger involved in mitochondrial biogenesis in muscle, we determined the effects of the Ca(2+) ionophore A-23187 on the expression of nuclear- and mitochondrially encoded genes. Treatment of myotubes with 1 microM A-23187 for 48-96 h increased...

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Identifiers

PMID: 15075204
DOI: 10.1152/ajpcell.00418.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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