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Article

Increased male reproductive success in Ts65Dn "Down syndrome" mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2010

Moore Clara S, Hawkins Charles, Franca Arianna, Lawler Ann, Devenney Benjamin, Das Ishita, Reeves Roger H

Abstract excerpt

The Ts65Dn mouse is trisomic for orthologs of about half the genes on Hsa21. A number of phenotypes in these trisomic mice parallel those in humans with trisomy 21 (Down syndrome), including cognitive deficits due to hippocampal malfunction that are sufficiently similar to human that "therapies"...

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Identifiers

PMID: 21110029
DOI: 10.1007/s00335-010-9300-8
PMCID: PMC3002156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21110029-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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