Article
Long contiguous stretches of homozygosity in the human genome.
Human mutation - 1 Nov 2006
Li Ling-Hui, Ho Sheng-Feng, Chen Chien-Hsiun, Wei Chun-Yu, Wong Wan-Ching, Li Li-Ying, Hung Shuen-Iu, Chung Wen-Hung, Pan Wen-Han, Lee Ming-Ta M, Tsai Fuu-Jen, Chang Ching-Fen, Wu Jer-Yuarn, Chen Yuan-Tsong
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are the most common sequence variation in the human genome; they have been successfully used in mapping disease genes and more recently in studying population genetics and cancer genetics. In a population-based association study using high-density oligonucleotide arrays for whole-genome SNP genotyping, we discovered that in the genomes of unrelated Han Chinese, 34 out of 515...
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