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Article

A charge pair interaction between Arg282 in transmembrane segment 7 and Asp341 in transmembrane segment 8 of hPepT1.

Pharmaceutical research - 1 Jan 2007

Kulkarni Ashutosh A, Davies Daryl L, Links Jennifer S, Patel Leena N, Lee Vincent H L, Haworth Ian S

Abstract excerpt

PURPOSE: To determine whether R282 in transmembrane segment 7 (TMS7) of hPepT1 forms a salt bridge with D341 in TMS8. METHODS: Mutated hPepT1 transporters containing point mutations at R282 and/or D341 were transiently transfected into HEK293 cells. Their steady state expression and functional ac...

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Source

Identifiers

PMID: 17009102
DOI: 10.1007/s11095-006-9119-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17009102-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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