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Article

Val66Met functional polymorphism and serum protein level of brain-derived neurotrophic factor (BDNF) in acute episode of schizophrenia and depression.

Pharmacological reports : PR - 1 Feb 2018

Skibinska Maria, Groszewska Agata, Kapelski Pawel, Rajewska-Rager Aleksandra, Pawlak Joanna, Dmitrzak-Weglarz Monika, Szczepankiewicz Aleksandra, Twarowska-Hauser Joanna

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF) influences neuron differentiation during development as well as the synaptic plasticity and neuron survival in adulthood. BDNF has been implicated in the pathogenesis of schizophrenia and depression. Val66Met polymorphism and BDNF serum level are potential biomarkers in neuropsychiatric disorders. The aim of this study was to determine the effect of BDNF gene...

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Identifiers

PMID: 29331787
DOI: 10.1016/j.pharep.2017.08.002

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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