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Article

BDNF-related mutations in major depressive disorder: a systematic review.

Acta neuropsychiatrica - 1 Feb 2023

Hartig Johannes, Nemeş Bogdan

Abstract excerpt

OBJECTIVE: A better understanding of the genetic, molecular and cellular mechanisms of brain-derived neurotrophic factor (BDNF) and its association with neuroplasticity could play a pivotal role in finding future therapeutic targets for novel drugs in major depressive disorder (MDD). Because there are conflicting results regarding the exact role of BDNF polymorphisms in MDD still, we set out to systematically...

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Biomarkers
Depressive Disorder, Major
Mutation
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35993165
DOI: 10.1017/neu.2022.22

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