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Article

BDNF Genetic Variant and Its Genotypic Fluctuation in Major Depressive Disorder.

Behavioural neurology - 1 Jan 2021

Ferreira Fratelli Caroline, Willatan Siqueira Jhon, Rodrigues Gontijo Bruna, de Lima Santos Maurício, de Souza Silva Calliandra Maria, Rodrigues da Silva Izabel Cristina

Abstract excerpt

Major depressive disorder (MDD) still has an unknown etiology and mechanisms. Many studies have been conducted seeking to associate and understand the connection of different genetic variants to this disease. Researchers have extensively studied the brain-derived neurotrophic factor (BDNF) Val66Met genetic variant in MDD; yet, their findings remain inconsistent. This systematic review sought to verify the GG...

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Identifiers

PMID: 34760029
DOI: 10.1155/2021/7117613
PMCID: PMC8575598

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