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Article

Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus.

Journal of neuroimmunology - 1 May 1990

Blasi E, Barluzzi R, Bocchini V, Mazzolla R, Bistoni F

Abstract excerpt

A murine cell line (BV-2) has been generated by infecting primary microglial cell cultures with a v-raf/v-myc oncogene carrying retrovirus (J2). BV-2 cells expressed nonspecific esterase activity, phagocytic ability and lacked peroxidase activity. Such cells secreted lysozyme and, following appropriate stimulation, also interleukin 1 and tumor necrosis factor. Furthermore, BV-2 cells exhibited spontaneous...

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Source

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PMID: 2110186
DOI: 10.1016/0165-5728(90)90073-v

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GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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