Molecular cloning of a recombinant retrovirus carrying a mutated envAKR-mycMH2 fusion gene immortalizing cells of the monocytic-macrophage lineage.

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Article

Molecular cloning of a recombinant retrovirus carrying a mutated envAKR-mycMH2 fusion gene immortalizing cells of the monocytic-macrophage lineage.

Oncogene - 1 May 1994

Sassano M, Granucci F, Seveso M, Marconi G, Foti M, Ricciardi-Castagnoli P

Abstract excerpt

The VN-11 recombinant retroviruses, originally generated by co-transfection of the avian MH2 and AKRv viral genomes, were molecularly cloned from an infected mouse cell line named N11. The analysis of the proviral genome sequence from one of these recombinants showed a possible envAKR-mycMH2 fusi...

Topics

Animals
Base Sequence
Cell Division
Cell Line
Cloning, Molecular
Genes, env
Genes, myc
Genome, Viral
Macrophages
Mice
Molecular Sequence Data
Monocytes
Mutation
Retroviridae

Source

Open in PubMed

Identifiers

PMID: 8152810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8152810-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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