Article
Mouse microglial cell lines differing in constitutive and interferon-gamma-inducible antigen-presenting activities for naive and memory CD4+ and CD8+ T cells.
Journal of neuroimmunology - 31 Dec 1995
Walker W S, Gatewood J, Olivas E, Askew D, Havenith C E
Abstract excerpt
We developed a panel of non-virus transformed cell lines derived from individual microglial precursors residing in the brains of normal mice. These colony stimulating factor-1-dependent cell lines are B7-1+ (CD80), Mac-1+, Mac-2+, Mac-3+, CD45+, MHC class I+, colony stimulating factor-1 receptor+...
Topics
- Adjuvants, Immunologic
- Animals
- Antigen Presentation
- Antigens, Viral
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Cell Line
- Hemocyanins
- Hybridomas
- Immunologic Memory
- Interferon-gamma
- Isoantigens
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Transgenic
- Microglia
- Phagocytosis
