Article
p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition.
Journal of cell science - 15 Dec 2010
Strippoli Raffaele, Benedicto Ignacio, Foronda Miguel, Perez-Lozano Maria Luisa, Sánchez-Perales Sara, López-Cabrera Manuel, Del Pozo Miguel Ángel
Abstract excerpt
Epithelial-to-mesenchymal transition (EMT) of peritoneal mesothelial cells is a pathological process that occurs during peritoneal dialysis. EMT leads to peritoneal fibrosis, ultrafiltration failure and eventually to the discontinuation of therapy. Signaling pathways involved in mesothelial EMT a...
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