Article
Activation of epidermal growth factor receptor results in Snail protein but not mRNA overexpression in endometrial cancer
13 Oct 2008
Abstract excerpt
Reduced E-cadherin expression is associated with tumour progression of many carcinomas, including endometrial cancers. The transcription factor Snail is known as one of the most prominent transcriptional E-cadherin repressors; its regulation in cancer tissues, however, still remains unclear. Here, we report that activation of epidermal growth factor receptor (EGFR) resulted in overexpression of Snail and also...
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