Article
High hyperdiploid childhood acute lymphoblastic leukemia
4 May 2009
Abstract excerpt
High hyperdiploidy (51-67 chromosomes) is the most common cytogenetic abnormality pattern in childhood B-cell precursor acute lymphoblastic leukemia (ALL), occurring in 25-30% of such cases. High hyperdiploid ALL is characterized cytogenetically by a nonrandom gain of chromosomes X, 4, 6, 10, 14, 17, 18, and 21 and clinically by a favorable prognosis. Despite the high frequency of this karyotypic subgroup, many...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
