Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Control of chromatin structure by spt6: different consequences in coding and regulatory regions.

Molecular and cellular biology - 1 Feb 2011

Ivanovska Iva, Jacques Pierre-Étienne, Rando Oliver J, Robert François, Winston Fred

Abstract excerpt

Spt6 is a highly conserved factor required for normal transcription and chromatin structure. To gain new insights into the roles of Spt6, we measured nucleosome occupancy along Saccharomyces cerevisiae chromosome III in an spt6 mutant. We found that the level of nucleosomes is greatly reduced across some, but not all, coding regions in an spt6 mutant, with nucleosome loss preferentially occurring over highly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Assembly and Disassembly
Share to Chromosomes, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histone Chaperones

Share to Nucleosomes

Share to Regulatory Sequences, Nucleic Acid

Share to RNA Polymerase II

Share to Serine

Share to Transcriptional Elongation Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 21098123
DOI: 10.1128/MCB.01068-10
PMCID: PMC3028613

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Control of chromatin structure by spt6: different consequences in coding and regulatory regions.PMID 21098123Read ↗

Evidence that Spt6p controls chromatin structure by a direct interaction with histones.Semantic proximity Read ↗

Intergenic transcription causes repression by directing nucleosome assembly.Semantic proximity Read ↗

Structure and biological importance of the Spn1-Spt6 interaction, and its regulatory role in nucleosome binding.Semantic proximity Read ↗

A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organization.Semantic proximity Read ↗

Transcription elongation factors repress transcription initiation from cryptic sites.Semantic proximity Read ↗

A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation.Semantic proximity Read ↗

Identification of histone mutants that are defective for transcription-coupled nucleosome occupancy.Semantic proximity Read ↗

Noncoding Transcription Is a Driving Force for Nucleosome Instability in spt16 Mutant Cells.Semantic proximity Read ↗

Global regulation by the yeast Spt10 protein is mediated through chromatin structure and the histone upstream activating sequence elements.Semantic proximity Read ↗

Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Charged residues on the side of the nucleosome contribute to normal Spt16-gene interactions in budding yeast.Semantic proximity Read ↗

Mutations in the SPT4, SPT5, and SPT6 genes alter transcription of a subset of histone genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.