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Article

Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients.

The Annals of thoracic surgery - 1 Dec 2010

Phillippi Julie A, Eskay Michael A, Kubala Adam A, Pitt Bruce R, Gleason Thomas G

Abstract excerpt

BACKGROUND: The mechanisms governing extracellular matrix degradation and smooth muscle cell (SMC) loss in the ascending aorta of bicuspid aortic valve (BAV) patients are unknown. We recently reported that expression and induction of metallothionein, a reactive oxygen species scavenger, is reduce...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21095332
DOI: 10.1016/j.athoracsur.2010.07.069
PMCID: PMC8172083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21095332-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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