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Article

Migration and growth are attenuated in vascular smooth muscle cells with type VIII collagen-null alleles.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2006

Adiguzel Eser, Hou Guangpei, Mulholland Diane, Hopfer Ulrike, Fukai Naomi, Olsen Bjorn, Bendeck Michelle

Abstract excerpt

OBJECTIVE: Type VIII collagen is upregulated after vascular injury and in atherosclerosis. However, the role of type VIII collagen endogenously expressed by smooth muscle cells (SMCs) and in the context of the vascular matrix microenvironment, which is rich in type I collagen, is not known. To address this, we have compared aortic SMCs from wild-type (WT) mice to SMCs from type VIII collagen-deficient (KO) mice...

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Source

Identifiers

PMID: 16269661
DOI: 10.1161/01.ATV.0000194155.96456.b7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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