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Article

Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm.

Cardiovascular research - 1 Nov 2013

Branchetti Emanuela, Poggio Paolo, Sainger Rachana, Shang Eric, Grau Juan B, Jackson Benjamin M, Lai Eric K, Parmacek Michael S, Gorman Robert C, Gorman Joseph H, Bavaria Joseph E, Ferrari Giovanni

Abstract excerpt

AIMS: Dissection and rupture of the ascending aorta are life-threatening conditions resulting in 80% mortality. Ascending aortic replacement in patients presenting with thoracic aortic aneurysm (TAA) is determined by metric measurement. However, a significant number of dissections occur outside of the parameters suggested by the current guidelines. We investigate the correlation among altered haemodynamic...

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Source

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Identifiers

PMID: 23985903
DOI: 10.1093/cvr/cvt205
PMCID: PMC4192047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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