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Article

Cellular phenotype transformation occurs during thoracic aortic aneurysm development.

The Journal of thoracic and cardiovascular surgery - 1 Sept 2010

Jones Jeffrey A, Zavadzkas Juozas A, Chang Eileen I, Sheats Nina, Koval Christine, Stroud Robert E, Spinale Francis G, Ikonomidis John S

Abstract excerpt

OBJECTIVE: Thoracic aortic aneurysms result from dysregulated remodeling of the vascular extracellular matrix, which may occur as a result of altered resident cellular function. The present study tested the hypothesis that aortic fibroblasts undergo a stable change in cellular phenotype during th...

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Source

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Identifiers

PMID: 20219212
DOI: 10.1016/j.jtcvs.2009.12.033
PMCID: PMC2901416

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20219212-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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