Article
Differential tensile strength and collagen composition in ascending aortic aneurysms by aortic valve phenotype.
The Annals of thoracic surgery - 1 Dec 2013
Pichamuthu Joseph E, Phillippi Julie A, Cleary Deborah A, Chew Douglas W, Hempel John, Vorp David A, Gleason Thomas G
Abstract excerpt
BACKGROUND: Ascending thoracic aortic aneurysm (ATAA) predisposes patients to aortic dissection and has been associated with diminished tensile strength and disruption of collagen. Ascending thoracic aortic aneurysms arising in patients with bicuspid aortic valve (BAV) develop earlier than in those with tricuspid aortic valves (TAV) and have a different risk of dissection. The purpose of this study was to compare...
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