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Article

The ascending aorta of male hypertensive bicuspid aortic valve patients preferentially associated with a cellular aneurysmal phenotype.

Physiological reports - 1 Apr 2022

Bergeron Alexandre, Hertig Vanessa, Villeneuve Louis, Chauvette Vincent, El-Hamamsy Ismail, Calderone Angelino

Abstract excerpt

Male sex and hypertension represent risk factors in the progression of an aortic aneurysm. The present study examined the morphological/cellular phenotype of the ascending aorta (AA) of male and female patients diagnosed with a bicuspid aortic valve (BAV) to test the hypothesis that hypertension-induced remodeling of male BAV patients preferentially recapitulated the expression of a panel of proteins favoring...

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Identifiers

PMID: 35439345
DOI: 10.14814/phy2.15251
PMCID: PMC9017972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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