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Article

Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation.

Molecular genetics and metabolism - 1 Feb 2011

Feng Qiping, Kalari Krishna, Fridley Brooke L, Jenkins Gregory, Ji Yuan, Abo Ryan, Hebbring Scott, Zhang Jianping, Nye Monica D, Leeder J Steven, Weinshilboum Richard M

Abstract excerpt

Betaine-homocysteine methyltransferase (BHMT) catalyzes the remethylation of homocysteine. BHMT is highly expressed in the human liver. In the liver, BHMT catalyzes up to 50% of homocysteine metabolism. Understanding the relationship between BHMT genetic polymorphisms and function might increase...

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Source

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Identifiers

PMID: 21093336
DOI: 10.1016/j.ymgme.2010.10.010
PMCID: PMC3053054

Genes

BHMT
BHMT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21093336-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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