Article
Phenotypes and mechanisms in the transformation of hematopoietic cells.
International journal of cell cloning - 1 Jan 1990
Ihle J N, Morishita K, Bartholomew C, Matsugi T, Askew D
Abstract excerpt
Interleukin 3 (IL-3) is a growth factor that supports the proliferation of early hematopoietic stem cells, as well as cells that are committed to a variety of the myeloid lineages. The mechanisms by which IL-3 functions have been studied through the use of a series of IL-3-dependent cell lines isolated from myeloid leukemias or long-term bone marrow cultures. A variety of studies have implicated tyrosine...
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