Article
Phenotypes and mechanisms in the transformation of hematopoietic cells.
International journal of cell cloning - 1 Jan 1990
Ihle J N, Morishita K, Bartholomew C, Matsugi T, Askew D
Abstract excerpt
Interleukin 3 (IL-3) is a growth factor that supports the proliferation of early hematopoietic stem cells, as well as cells that are committed to a variety of the myeloid lineages. The mechanisms by which IL-3 functions have been studied through the use of a series of IL-3-dependent cell lines is...
Topics
- Animals
- Cell Transformation, Neoplastic
- DNA-Binding Proteins
- Hematopoietic Stem Cells
- Humans
- Leukemia, Myeloid
- Metalloproteins
- Phenotype
- Protein-Tyrosine Kinases