JAK3: expression and mapping to chromosome 19p12-13.1.

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Article

JAK3: expression and mapping to chromosome 19p12-13.1.

Experimental hematology - 1 May 1997

Safford M G, Levenstein M, Tsifrina E, Amin S, Hawkins A L, Griffin C A, Civin C I, Small D

Abstract excerpt

We cloned JAK3, the most recently described member of the JAK family of intracellular tyrosine kinases, from normal human CD34+ RNA. JAK3 is involved in the signal transduction pathways of the IL-2, IL-4, IL7, IL-9, and IL-15 receptors by association with their common gamma-chain (gamma[c]). JAK3...

Topics

Adult
Amino Acid Sequence
Animals
Antigens, CD34
Base Sequence
Bone Marrow
Bone Marrow Cells
Chromosome Mapping
Chromosomes, Human, Pair 19
Clone Cells
Gene Expression
Genetic Variation
Humans
In Situ Hybridization, Fluorescence
Janus Kinase 3
Male
Molecular Sequence Data
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 9168059

Genes

JAK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9168059-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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