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Article

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease.

Nature reviews. Neuroscience - 1 Dec 2010

Cookson Mark R

Abstract excerpt

Parkinson's disease, like many common age-related conditions, is now recognized to have a substantial genetic component. Here, I discuss how mutations in a large complex gene--leucine-rich repeat kinase 2 (LRRK2)--affect protein function, and I review recent evidence that LRRK2 mutations affect p...

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Identifiers

PMID: 21088684
DOI: 10.1038/nrn2935
PMCID: PMC4662256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21088684-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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