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Article

Urokinase receptor mediates mobilization, migration, and differentiation of mesenchymal stem cells

18 Nov 2010

Abstract excerpt

AIMS: Multipotent mesenchymal stem cells (MSCs) have regenerative properties and are recognized as putative players in the pathogenesis of cardiovascular diseases. The underlying molecular mechanisms remain, however, sparsely explored. Our study was designed to elucidate a probable role for the multifunctional urokinase (uPA)/urokinase receptor (uPAR) system in MSC regulation. Though uPAR has been implicated in a...

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PMID: 21088115
DOI: 10.1093/cvr/cvq362

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