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Article

Cell-based analysis of structure-function activity of threonine aspartase 1.

The Journal of biological chemistry - 28 Jan 2011

Bier Carolin, Knauer Shirley K, Klapthor Alexander, Schweitzer Andrea, Rekik Alexander, Krämer Oliver H, Marschalek Rolf, Stauber Roland H

Abstract excerpt

Taspase1 is a threonine protease responsible for cleaving intracellular substrates. As such, (de)regulated Taspase1 function is expected not only to be vital for ordered development but may also be relevant for disease. However, the full repertoires of Taspase1 targets as well as the exact biochemical requirements for its efficient and substrate-specific cleavage are not yet resolved. Also, no cellular assays for...

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Identifiers

PMID: 21084304
DOI: 10.1074/jbc.M110.161646
PMCID: PMC3024795

Genes

NXF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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