Article
Bioinformatics Analysis of the Subcellular Distribution of the Human Serpin Superfamily Reveals Putative Nuclear Localization and Nuclear Export Signals, Suggesting Potential Intracellular Roles of Interest
2025-10-15
Abstract excerpt
The serpin (serine protease inhibitor) superfamily is the largest class of protease inhibitors, involved in proteolytic cascades and mostly serving as serine/cysteine proteinase inhibitors. Serpins are involved in various biological functions: coagulation, fibrinolysis, angiogenesis, and have crucial roles in various diseases, including cardiac fibrosis, Alzheimer’s, emphysema, obesity, and diabetes. Based on the...
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Identifiers and source
- Literature Corpus work
- da92002d-a3f9-5a23-a438-569a7bba8999
- DOI
- 10.20944/preprints202510.1146.v1